Coffee enemas
Mechanisms:
Estimated cost: $10 a month, after getting about $20 equipment (coffee grinder and enema bulb)
Science:
Dr. Nicholas Gonzalez on coffee enemas in trials for cancer
YouTube video - Do coffee enemas work?
Dr. Pawl's comment on boosting glutathione-s-transferase in NF:
"The fundamental defect in NF is a mutant variety of the protein neurofibromin (NM) which normally inhibits Ras, a potent activator of cell growth and proliferation. Left unchecked Ras leads to overgrowth in Schwann cells causing the tumors characteristic of NF.
Glutathione S-transferase (GST) is an enzyme that works with glutathione (GTH). This activity is useful in the detoxification of endogenous compounds such as peroxidised lipids, as well as the metabolism of xenobiotics. As well as their enzymatic activities, GST may also bind toxins and function as transport proteins. One critical activity of GST is the inhibition of Ras.
Our product increases GTH which is a cofactor for GST activity. Increasing GST activity may help suppress the over expression of Ras present in patients with NF and the mutant NM.
At this time we are currently in the study phase to better determine the effects of NeuropathyRx® on Neurofibromatosis."
--CTF.org
We can't all afford glutathione IVs, and some people have negative reactions to glutathione, but coffee enemas do something very similar without those costs and problems.
What you need to know is:
Toxins
Toxins do seem to have a role in tumorigenesis. They might interact with PAK.
So reducing toxins through coffee enemas could potentially help.
"I am not an expert on NF1/ NF2 but it appears that certain TOXINS and ESTROGENS seem to activate PAK, or maybe it knocks out the body's ability to regulate PAK which ever the case may be, it starts what appears to be a vicious ongoing cycle. Clearly avoiding and getting the toxins out seems to make sense. "--NF Thread on Dr. Eddy's Clinic Forum
Glutathione has been indicated as potentially helpful for NF. NAC, a glutathione precursor is sometimes recommended for NF. And again, glutathione-s-transferase has anti-tumor effects, for example:
Glutathione-S-Transferase as a selective inhibitor of oncogenic ras-p21-induced mitogenic signaling through blockade of activation of jun by jun-N-terminal kinase.
More information on how it works:
"In an interview Gerhard Wolter, M.D., outlined the rationale for giving coffee enemas. He explained that when coffee is given in the form of an enema, the caffeine is absorbed through the rectal mucosa and is transported directly to the liver, where it causes a dilation of the bile ducts. This increases the elimination of toxins from the liver. Occasionally a "healing crisis" is produced by an overload of toxins being released into the duodenum and small intestines. In these cases, large amounts of peppermint tea can be used to dilute and wash the noxious bile out of the intestines. (11)
Recent research shows that certain chemicals in coffee called palmitates stimulate an important liver enzyme called glutathione-S-transferase, which is capable of removing a variety of free radicals from the bloodstream. A coffee enema increases the glutathione-S-transferase enzyme activity in the liver from 600 percent to 700 percent above normal. During the time that the coffee enema is being held in, all the blood in the body passes through the liver at least five times, since all the blood in the body goes through the liver every three minutes.
Other chemicals in coffee, including caffeine, theobromine, and theophylline, cause blood vessels and bile ducts to dilate, increasing the elimination of toxic bile. Additionally, some of the water absorbed through the intestinal wall goes directly to the liver, diluting the bile and increasing the bile flow.
A choleretic is any substance that causes bile flow. The coffee enema is the only pharmaceutically effective choleretic noted in the medical literature that can be safely used many times daily without toxic effects. (11)"
-Gerson Therapy in Neurofibromatosis FAQ on CureZone
How to do coffee enemas
There are plenty of instructions online. It's not hard.
Basic coffee enema instructions
A rectal enema bulb is a lot easier to clean than the large bags.
This is one with a wide opening that makes it easy to clean.
Rectal enema bulb
These feel good. it feels great to be detoxified. They are also a nice time to relax, since you need to lie on the floor while doing them.
Kevin Gianni talk on how coffee enemas work
Once they get over the gross factor, many people end up counting coffee enemas among their favorite treatments.
People who are caffeine-sensitive should do these early in the day, because the caffeine can disturb sleep.
Mechanisms:
- Increase glutathione-s-transferase
- Inhibit Ras
- Rectal administration (high absorption) of potent Nrf2 activators from coffee, cafestol and kahweol
- Decrease environmental toxins in the body
- Decrease xenobiotics
- Highly rated by patients with detoxification disorders (MCS, CFS, Lyme disease, etc.) as a method to increase detoxification
Estimated cost: $10 a month, after getting about $20 equipment (coffee grinder and enema bulb)
Science:
Dr. Nicholas Gonzalez on coffee enemas in trials for cancer
YouTube video - Do coffee enemas work?
Dr. Pawl's comment on boosting glutathione-s-transferase in NF:
"The fundamental defect in NF is a mutant variety of the protein neurofibromin (NM) which normally inhibits Ras, a potent activator of cell growth and proliferation. Left unchecked Ras leads to overgrowth in Schwann cells causing the tumors characteristic of NF.
Glutathione S-transferase (GST) is an enzyme that works with glutathione (GTH). This activity is useful in the detoxification of endogenous compounds such as peroxidised lipids, as well as the metabolism of xenobiotics. As well as their enzymatic activities, GST may also bind toxins and function as transport proteins. One critical activity of GST is the inhibition of Ras.
Our product increases GTH which is a cofactor for GST activity. Increasing GST activity may help suppress the over expression of Ras present in patients with NF and the mutant NM.
At this time we are currently in the study phase to better determine the effects of NeuropathyRx® on Neurofibromatosis."
--CTF.org
We can't all afford glutathione IVs, and some people have negative reactions to glutathione, but coffee enemas do something very similar without those costs and problems.
What you need to know is:
- Coffee enemas powerfully stimulate glutathione-s-transferase. Which is not only great for detoxification, but also a Ras inhibitor.
- People use coffee enemas as part of the Gerson protocol for cancer, a natural cancer therapy. So perhaps that detoxification and Ras inhibition is getting somewhere for them. See the documentary The Beautiful Truth for more information on the Gerson protocol for cancer.
- IMPORTANT: Lots of coffee is high in mycotoxins, which are carcinogenic. Not exacly what you want to be putting into body cavities if you are trying to avoid tumors. This article discusses where to find low-mycotoxin coffee. Low-Mycotoxin Coffee Brands
- This is the coffee brand I use (no affiliation): Topeca Manzano Microlot
Toxins
Toxins do seem to have a role in tumorigenesis. They might interact with PAK.
So reducing toxins through coffee enemas could potentially help.
"I am not an expert on NF1/ NF2 but it appears that certain TOXINS and ESTROGENS seem to activate PAK, or maybe it knocks out the body's ability to regulate PAK which ever the case may be, it starts what appears to be a vicious ongoing cycle. Clearly avoiding and getting the toxins out seems to make sense. "--NF Thread on Dr. Eddy's Clinic Forum
Glutathione has been indicated as potentially helpful for NF. NAC, a glutathione precursor is sometimes recommended for NF. And again, glutathione-s-transferase has anti-tumor effects, for example:
Glutathione-S-Transferase as a selective inhibitor of oncogenic ras-p21-induced mitogenic signaling through blockade of activation of jun by jun-N-terminal kinase.
More information on how it works:
"In an interview Gerhard Wolter, M.D., outlined the rationale for giving coffee enemas. He explained that when coffee is given in the form of an enema, the caffeine is absorbed through the rectal mucosa and is transported directly to the liver, where it causes a dilation of the bile ducts. This increases the elimination of toxins from the liver. Occasionally a "healing crisis" is produced by an overload of toxins being released into the duodenum and small intestines. In these cases, large amounts of peppermint tea can be used to dilute and wash the noxious bile out of the intestines. (11)
Recent research shows that certain chemicals in coffee called palmitates stimulate an important liver enzyme called glutathione-S-transferase, which is capable of removing a variety of free radicals from the bloodstream. A coffee enema increases the glutathione-S-transferase enzyme activity in the liver from 600 percent to 700 percent above normal. During the time that the coffee enema is being held in, all the blood in the body passes through the liver at least five times, since all the blood in the body goes through the liver every three minutes.
Other chemicals in coffee, including caffeine, theobromine, and theophylline, cause blood vessels and bile ducts to dilate, increasing the elimination of toxic bile. Additionally, some of the water absorbed through the intestinal wall goes directly to the liver, diluting the bile and increasing the bile flow.
A choleretic is any substance that causes bile flow. The coffee enema is the only pharmaceutically effective choleretic noted in the medical literature that can be safely used many times daily without toxic effects. (11)"
-Gerson Therapy in Neurofibromatosis FAQ on CureZone
How to do coffee enemas
There are plenty of instructions online. It's not hard.
Basic coffee enema instructions
A rectal enema bulb is a lot easier to clean than the large bags.
This is one with a wide opening that makes it easy to clean.
Rectal enema bulb
These feel good. it feels great to be detoxified. They are also a nice time to relax, since you need to lie on the floor while doing them.
Kevin Gianni talk on how coffee enemas work
Once they get over the gross factor, many people end up counting coffee enemas among their favorite treatments.
People who are caffeine-sensitive should do these early in the day, because the caffeine can disturb sleep.
